CHEM 125a - Lecture 34 - Sharpless Oxidation Catalysts and the Conformation of Cycloalkanes

Lecture 34 - Sharpless Oxidation Catalysts and the Conformation of Cycloalkanes

Overview

Professor Barry Sharpless of Scripps describes the Nobel-prizewinning development of titanium-based catalysts for stereoselective oxidation, the mechanism of their reactions, and their use in preparing esomeprazole. Conformational energy of cyclic alkanes illustrates the use of molecular mechanics.

Resources

Professor McBride's web resources for CHEM 125 (Fall 2008)

http://webspace.yale.edu/chem125_oyc/#L34

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Assignment

Reading assignments, problem sets, PowerPoint presentations, and other resources for this lecture can be accessed from Professor McBride's on-campus course website, which was developed for his Fall 2008 students. Please see Resources section below.

Course Media

Transcript

html

Audio

mp3

Low Bandwidth Video

mov [100MB]

High Bandwidth Video

mov [500MB]