CHEM 125a - Lecture 26 - Van't Hoff's Tetrahedral Carbon and Chirality

Lecture 26 - Van't Hoff's Tetrahedral Carbon and Chirality


With his tetrahedral carbon models van't Hoff explained the mysteries of known optical isomers possessing stereogenic centers and predicted the existence of chiral allenes, a class of molecules that would not be observed for another sixty-one years. Symmetry operations that involve inverting an odd number of coordinate axes interconvert mirror-images. Like printed words, only a small fraction of molecules are achiral. Verbal and pictorial notation for stereochemistry are discussed.


Professor McBride's web resources for CHEM 125 (Fall 2008)

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Reading assignments, problem sets, PowerPoint presentations, and other resources for this lecture can be accessed from Professor McBride's on-campus course website, which was developed for his Fall 2008 students. Please see Resources section below.

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