CHEM 125a - Lecture 25 - Models in 3D Space (1869-1877); Optical Isomers

Lecture 25 - Models in 3D Space (1869-1877); Optical Isomers

Overview

Despite cautions from their conservative elders, young chemists like Paternó and van't Hoff began interpreting molecular graphs in terms of the arrangement of a molecule's atoms in 3-dimensional space. Benzene was one such case, but still more significant was the prediction, based on puzzling isomerism involving "optical activity," that molecules could be "chiral," that is, right- or left-handed. Louis Pasteur effected the first artificial separation of racemic acid into tartaric acid and its mirror-image.

Resources

Professor McBride's web resources for CHEM 125 (Fall 2008)

http://webspace.yale.edu/chem125_oyc/#L25

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Assignment

Reading assignments, problem sets, PowerPoint presentations, and other resources for this lecture can be accessed from Professor McBride's on-campus course website, which was developed for his Fall 2008 students. Please see Resources section below.

Course Media

Transcript

html

Audio

mp3

Low Bandwidth Video

mov [100MB]

High Bandwidth Video

mov [500MB]